ERLIN1 Mouse anti-Human, Clone: OTI4C11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF809151

Catalog No. 50-166-9308

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.

Specifications

• Antigen: ERLIN1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ERLIN1
• Gene Alias: C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10613
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI4C11
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O75477
• Gene Symbols: ERLIN1
• Immunogen: Human recombit protein fragment corresponding to amino acids 107-346 of human ERLIN1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1