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Invitrogen™ ERLIN1 Polyclonal Antibody
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Catalog No. PIPA590076
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PIPA590076 100 μL
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Catalog No. PIPA590076 Supplier Invitrogen™ Supplier No. PA590076
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KADAEYYAAH KYATSNKHKL TPEYLELKKY QAIASNSKIY FGSNIPNMFV DSSCALKYSD IRTGRESSLP SKEALEPSGE NVIQNKESTG; Positive Samples: 293T, HepG2, BxPC3, DU145, OVCAR-3, Mouse kidney, Rat testis; Cellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein.

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERLIN1
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Erlin1
Gene Accession No. O75477, Q91X78
Gene Alias 2810439N09Rik; Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; C10orf69; C80197; endoplasmic reticulum lipid raft-associated protein 1; ER lipid raft associated 1; Erlin1; erlin-1; KE04; Keo4; OTTHUMP00000059425; OTTHUMP00000197867; Protein KE04; Protein KE04 homolog; RGD1307058; SPFH domain family, member 1; SPFH domain-containing protein 1; Spfh1; SPG62; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Gene Symbols Erlin1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_0064502).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10613, 226144, 293939
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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