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ERLIN2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 147811AP150UL

Encompass_Preferred

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Catalog No. 50-172-9716


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Description

Description

ERLIN2, also named as C8orf2 and SPFH2, is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1. It promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. ERLIN2 is involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. The MW of ERLIN1/ERLIN2 complex is about 70 kDa.
Specifications

Specifications

ERLIN2
Polyclonal
Unconjugated
ERLIN2
C8orf2, ER lipid raft associated 2, Erlin 2, ERLIN2, NET32, SPFH2
Rabbit
Antigen Affinity Chromatography
RUO
11160, 244373, 290823
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
B5DEH2, O94905, Q8BFZ9
Erlin2
ERLIN2 Fusion Protein Ag6369
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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