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Invitrogen™ ERMAP Monoclonal Antibody (767505)
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Catalog No. PIMA524371
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100 μg
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Catalog No. Quantity
PIMA524371 100 μg
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Catalog No. PIMA524371 Supplier Invitrogen™ Supplier No. MA524371
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Description

Mouse Monoclonal Antibody

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Erythroblast membrane-associated protein (ERMAP) is a gene situated on chromosome 1p34.2, encoding a protein primarily associated with erythroblast cells. ERMAP is expressed in erythroid lineage cells and plays a crucial role as an adhesion molecule, involved in the maturation and stability of the erythrocyte membrane. This protein is associated with the Scianna blood group system, and variations within the ERMAP gene lead to different antigenic expressions which are important in transfusion medicine. ERMAP is also significant in mediating cell-cell adhesion processes essential for erythropoiesis, where it facilitates receptor-ligand interactions in hematopoietic stem cells. Mutations or polymorphisms in ERMAP can result in altered blood group antigens, impacting blood transfusion compatibility and potentially leading to hemolytic reactions. Given its distinct role in erythrocyte formation, ERMAP is a subject of interest for further research into blood-related disorders and their genetic underpinnings.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERMAP
Applications Flow Cytometry
Classification Monoclonal
Clone 767505
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene ERMAP
Gene Accession No. Q96PL5
Gene Alias AA409279; AI666418; BTN5; ERMAP; erythroblast membrane associated protein (Scianna blood group); erythroblast membrane-associated protein; erythroblast membrane-associated protein (Scianna blood group); erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; PRO2801; Radin blood group; Radin blood group (Rd); radin blood group antigen; RD; RDMGC118812; SC; Scianna blood group; Scianna blood group (Sc); scianna blood group antigen; SCMGC118813
Gene Symbols ERMAP
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human ERMAP His30-Ala155.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114625
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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