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Invitrogen™ ERMAP Monoclonal Antibody (OTIC8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525042

Catalog No. PIMA525042


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Description

Description

ERMAP Monoclonal Antibody for ICC/IF, Flow

Erythroblast membrane-associated protein (ERMAP) is a gene situated on chromosome 1p34.2, encoding a protein primarily associated with erythroblast cells. ERMAP is expressed in erythroid lineage cells and plays a crucial role as an adhesion molecule, involved in the maturation and stability of the erythrocyte membrane. This protein is associated with the Scianna blood group system, and variations within the ERMAP gene lead to different antigenic expressions which are important in transfusion medicine. ERMAP is also significant in mediating cell-cell adhesion processes essential for erythropoiesis, where it facilitates receptor-ligand interactions in hematopoietic stem cells. Mutations or polymorphisms in ERMAP can result in altered blood group antigens, impacting blood transfusion compatibility and potentially leading to hemolytic reactions. Given its distinct role in erythrocyte formation, ERMAP is a subject of interest for further research into blood-related disorders and their genetic underpinnings.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ERMAP
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q96PL5
ERMAP
Full length human recombinant protein of ERMAP produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Flow Cytometry, Immunocytochemistry
OTIC8
Unconjugated
ERMAP
AA409279; AI666418; BTN5; ERMAP; erythroblast membrane associated protein (Scianna blood group); erythroblast membrane-associated protein; erythroblast membrane-associated protein (Scianna blood group); erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; PRO2801; Radin blood group; Radin blood group (Rd); radin blood group antigen; RD; RDMGC118812; SC; Scianna blood group; Scianna blood group (Sc); scianna blood group antigen; SCMGC118813
Mouse
Affinity Chromatography
RUO
114625
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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