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Invitrogen™ ERMAP Polyclonal Antibody
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Catalog No. PIPA560029
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100 μL
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PIPA560029 100 μL
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Catalog No. PIPA560029 Supplier Invitrogen™ Supplier No. PA560029
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PLVICSELHK SEESIVPRPE GKGHANGDVS LKVNSSLLPP KAPELKDIIL SLPPDLGPAL QELKAPS Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 64%.

Erythroblast membrane-associated protein (ERMAP) is a gene situated on chromosome 1p34.2, encoding a protein primarily associated with erythroblast cells. ERMAP is expressed in erythroid lineage cells and plays a crucial role as an adhesion molecule, involved in the maturation and stability of the erythrocyte membrane. This protein is associated with the Scianna blood group system, and variations within the ERMAP gene lead to different antigenic expressions which are important in transfusion medicine. ERMAP is also significant in mediating cell-cell adhesion processes essential for erythropoiesis, where it facilitates receptor-ligand interactions in hematopoietic stem cells. Mutations or polymorphisms in ERMAP can result in altered blood group antigens, impacting blood transfusion compatibility and potentially leading to hemolytic reactions. Given its distinct role in erythrocyte formation, ERMAP is a subject of interest for further research into blood-related disorders and their genetic underpinnings.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERMAP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ERMAP
Gene Accession No. Q96PL5
Gene Alias AA409279; AI666418; BTN5; ERMAP; erythroblast membrane associated protein (Scianna blood group); erythroblast membrane-associated protein; erythroblast membrane-associated protein (Scianna blood group); erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; PRO2801; Radin blood group; Radin blood group (Rd); radin blood group antigen; RD; RDMGC118812; SC; Scianna blood group; Scianna blood group (Sc); scianna blood group antigen; SCMGC118813
Gene Symbols ERMAP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ERMAP. Recombinant protein control fragment (Product #RP-98529).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114625
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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