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Invitrogen™ ERN2 Polyclonal Antibody
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Catalog No. PIPA513921
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400 μL
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PIPA513921 400 μL
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Catalog No. PIPA513921 Supplier Invitrogen™ Supplier No. PA513921
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Description

Rabbit Polyclonal Antibody

ERN2 Polyclonal Antibody for Western Blot

ERN2 serine/threonine kinase or endoplasmic reticulum to nucleus signaling 2 protein is a human homologue of the yeast Ire1 gene product which plays a role in multiple facets of the ER stress response in mammalian cells. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERN2
Applications Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene ERN2
Gene Accession No. Q76MJ5
Gene Alias endoplasmic reticulum (ER) to nucleus signalling 2; endoplasmic reticulum to nucleus signaling 2; endoplasmic reticulum to nucleus signalling 2; endoplasmic reticulum-to-nucleus signaling 2; Endoribonuclease; ER to nucleus signalling 2; Ern1; ern2; hIRE2p; inositol-requiring 1 (Yeast homologue); inositol-requiring 1 beta; inositol-requiring protein 2; Ire1; IRE1 beta; IRE1, S. cerevisiae, homolog of; Ire1b; ire1-beta; IRE2; IRE2p; mIre1; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE2
Gene Symbols ERN2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2.
Purification Method Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10595
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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