Invitrogen™ ERp72 Polyclonal Antibody, Alexa Fluor™ 488

Catalog No.	Quantity
PIPA1007AX	50 μL

Catalog No. PIPA1007AX Supplier Invitrogen™ Supplier No. PA1007A488

Description

Rabbit Polyclonal Antibody

PA1007A488 detects ERp72 protein in human and mouse samples. The PA1007A488 immunogen is a synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of human ERp72. This peptide (Cat. # PEP-223) is available for use in neutralization and control experiments.

ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone.

Specifications

• Antigen: ERp72
• Applications: Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Alexa Fluor 488
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene: PDIA4
• Gene Accession No.: P08003, P13667
• Gene Alias: AI987846; caBP2; Cai; calcium binding protein, intestinal; calcium-binding protein 2; EC 5.3.4.1; endoplasmic reticulum protein 72; endoplasmic reticulum resident protein 70; Endoplasmic reticulum resident protein 72; ER protein 70; ER protein 72; Erp70; Erp72; ERp-72; PDIA4; protein disu; protein disulfide isomerase A4; protein disulfide isomerase associated 4; protein disulfide isomerase family A member 4; protein disulfide isomerase family A, member 4; protein disulfide isomerase related protein (calcium-binding protein, intestinal-related); protein disulfide isomerase-associated 4; protein disulfide-isomerase A4; Protein ERp-72; testicular tissue protein Li 137
• Gene Symbols: PDIA4
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of humna ERp72.
• Purification Method: Antigen affinity chromatography
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12304, 9601
• Target Species: Human, Mouse
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov