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Invitrogen™ ERRF Polyclonal Antibody
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Catalog No. PIPA555373
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100 μL
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PIPA555373 100 μL
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Catalog No. PIPA555373 Supplier Invitrogen™ Supplier No. PA555373
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLTRVTPMGG GCLAQARATL PLCRGSVASA SFPVSPLCPQ EVPEAKGKPV KAAPVRSSTW GTVKDSLKAL SSCVCGQ Highest antigen sequence identity to the following orthologs: Mouse - 42%, Rat - 30%.

The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERRF
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SRARP
Gene Accession No. Q8NEQ6
Gene Alias C1orf64; chromosome 1 open reading frame 64; ER-related factor; ERRF; Gm694; predicted gene 694; RP11-5P18.4; Srarp; SSPR; Steroid receptor-associated and regulated protein; Steroid receptor-regulated protein; uncharacterized protein C1orf64; uncharacterized protein C1orf64 homolog
Gene Symbols SRARP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ERRF. Recombinant protein control fragment (Product #RP-92440).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149563
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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