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Invitrogen™ ERRF Polyclonal Antibody
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Catalog No. PIPA534534
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100 μg
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Catalog No. Quantity
PIPA534534 100 μg
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Catalog No. PIPA534534 Supplier Invitrogen™ Supplier No. PA534534
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Hela cell lysate. PA5-34534 can be used with blocking peptide PEP-1577.

The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERRF
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SRARP
Gene Accession No. Q8NEQ6
Gene Alias C1orf64; chromosome 1 open reading frame 64; ER-related factor; ERRF; Gm694; predicted gene 694; RP11-5P18.4; Srarp; SSPR; Steroid receptor-associated and regulated protein; Steroid receptor-regulated protein; uncharacterized protein C1orf64; uncharacterized protein C1orf64 homolog
Gene Symbols SRARP
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human ERRF.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149563, 277744
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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