Erythromycin, ∽98%, MP Biomedicals™

Description

Erythromycin ∽98%, White Powder

• It Used in cell culture applications at approximately 100 mg/liter.
• Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth.
• Erythromycin resistance can be induced in bacteria.
• Erythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis.
• This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus.
• It is a mixture consisting largely of erythromycin A with lesser amounts of erythromycins B and C.

Specifications

Chemical Identifiers

• CAS: 114-07-8
• Molecular Formula: C37H67NO13
• Molecular Weight (g/mol): 733.94
• MDL Number: MFCD00084654
• InChI Key: ULGZDMOVFRHVEP-RWJQBGPGSA-N
• IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

• pH: 8.0 to 10.5 (70% aq soln)
• Melting Point: 135 to 140°C (literature)
• Extinction Coefficient: EM = 50 (280 nm, pH 6.3)
• Potency: ≥850 µg/mg
• Quantity: 25 g
• Optical Rotation: -71° to -78° (c=2, ethanol)
• Beilstein: 75279
• Synonym: E- mycin, Erycin, Robimysin, Erythrocin
• Solubility Information: Slightly soluble in water (∽2mg/mL); Moderately soluble in ether, ethylene dichloride, amyl acetate; freely soluble in alcohols (ethanol - 50mg/mL), acetone, chloroform, acetonitrile, ethyl acetate. Soluble in 2 M Hydrochloric acid (50mg/mL).
• Grade: ∽98%

Safety and Handling

RTECSNumber	KF4375000
storageNote1	Store at Room Temperature (15-30°C).