Thermo Scientific Chemicals (-)-Erythromycin, Eur.Ph.

Description

Erythromycin (E-Mycin or erythrocin), CAS # 114-07-8, is a broad-spectrum antibiotic.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Erythromycin is a macrolide antibiotic that works by binding the 50S ribosomal subunit and inhibiting polypeptide formation
• Erythromycin was isolated from Saccharopolyspora erythraea

Applications

• Erythromycin can be used to disrupt the growth of gram-positive and gram-negative bacteria
• Erythromycin has been shown to have motor effects in the gastrointestinal system and can be used for laboratory research on migrating motor complex activity

Specifications

Chemical Identifiers

• CAS: 114-07-8
• Molecular Formula: C37H67NO13
• Molecular Weight (g/mol): 733.94
• MDL Number: MFCD00084654
• InChI Key: ULGZDMOVFRHVEP-RWJQBGPGSA-N
• PubChem CID: 12560
• ChEBI: CHEBI:42355
• IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

• Type: (-)-Erythromycin
• Physical Form: Powder or Crystals
• Melting Point: 138.0°C to 140.0°C
• Infrared Spectrum: Authentic (Identification A)
• Packaging: Glass Bottle
• Specific Rotation: − 74.50 (20.00°C c=2,ethanol)
• Water: 6.5% max. (K.F.)
• Color: Colorless or White or Yellow
• Quantity: 5 g
• Solubility Information: Solubility in water: +/- 2 mg/mg. Other solubilities: freely soluble in alcohols, acetone, chloroform,, acetonitrile, ethyl acetate, moderately soluble in ether, ethylenedichloride, and amyl acetate
• Formula Weight: 733.94
• Percent Purity: 93.0 to 102.0% (sum of erythromycin A, B and C, on anhydrous substance); 5.0% max. erythromycin B and erythromycin C)
• Chemical Name or Material: (-)-Erythromycin

Safety and Handling

EINECSNumber	204-040-1
RTECSNumber	KF4375000
TSCA	TSCA

SDS

RUO – Research Use Only