Invitrogen™ ESAM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580599

Catalog No. PIPA580599

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Endothelial Cell Adhesion Molecule.

ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.

Specifications

• Antigen: ESAM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ESAM
• Gene Alias: 2310008D05Rik; endothelial cell adhesion molecule; endothelial cell-selective adhesion molecule; endothelial cell-specific adhesion molecule; Esam; Esam1; HUEL (C4orf1)-interacting protein; LP4791 protein; UNQ220/PRO246; W117m
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 90952
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q96AP7
• Gene Symbols: ESAM
• Immunogen: A synthetic peptide corresponding to the C-terminus of the Human Endothelial Cell Adhesion Molecule.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov