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Invitrogen™ ESAM Polyclonal Antibody
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Catalog No. PIPA588422
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100 μL
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PIPA588422 100 μL
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Catalog No. PIPA588422 Supplier Invitrogen™ Supplier No. PA588422
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QLQLHLPANR LQAVEGGEVV LPAWYTLHGE VSSSQPWEVP FVMWFFKQKE KEDQVLSYIN GVTTSKPGVS LVYSMPSRNL SLRLEGLQEK DSGPYSCSVN VQDKQGKSRG HSIKTLELNV LVPPAPPSCR LQGVPHVGAN VTLSCQSPRS KPAVQYQWDR QLPSFQTFFA PALDVIRGSL SLTNLSSSMA GVYVCKAHNE VGTAQCNVTL EVSTGPGAA; Positive Samples: HT-29, HepG2, 293T, A-549; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, adherens junction, tight junction.

ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ESAM
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ESAM
Gene Accession No. Q96AP7
Gene Alias 2310008D05Rik; endothelial cell adhesion molecule; endothelial cell-selective adhesion molecule; endothelial cell-specific adhesion molecule; Esam; Esam1; HUEL (C4orf1)-interacting protein; LP4791 protein; UNQ220/PRO246; W117m
Gene Symbols ESAM
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human ESAM (NP_6204112).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90952
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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