ESR1 Mouse anti-Human, Clone: , Abnova™

Catalog No.	Quantity
89-934-112	50 μL

Catalog No. 89-934-112 Supplier Abnova Corporation Supplier No. MAB12515

Description

Mouse monoclonal antibody raised against human ESR1.

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]

Specifications

• Antigen: ESR1
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against human ESR1.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:800) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.03% sodium azide).
• Gene Alias: DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1
• Gene Symbols: ESR1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 410-592 of human ESR1.
• Purification Method: Protein A purification
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2099
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1