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Esrp-2 Monoclonal Antibody (22C5.H7.A6), Rockland™
SDP

Mouse Monoclonal Antibody

$174.73 - $651.91

Specifications

Antigen Esrp-2
Clone 22C5.H7.A6
Concentration 1 mg/mL
Applications ELISA, Western Blot
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-1461
SDP
Encompass_Preferred
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Rockland Immunochemicals
210301C32
100 μg
Each for $651.91
Only null left
Add to Cart
 
50-199-1462
SDP
Encompass_Preferred
View Documents
Rockland Immunochemicals
210301C32S
25 μL
Each for $174.73
Only null left
Add to Cart
 
Description

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody reacts with mouse Esrp-2 protein. A BLAST analysis was used to suggest cross-reactivity with Esrp-2 from mouse based on a 100% homology with the immunizing sequence. Cross-reactivity with Esrp-2 from other sources has not been determined.

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
Specifications

Specifications

Esrp-2
1 mg/mL
Monoclonal
Liquid
RUO
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
9530027K23Rik; Epithelial splicing regulatory protein 2; Esrp2; PP7059; Rbm35b; RNA binding motif protein 35A; RNA binding motif protein 35b; RNA-binding motif protein 35B; RNA-binding protein 35B
ESRP2
IgG2a κ
-20°C, Avoid Freeze/Thaw Cycles
ESRP2
22C5.H7.A6
ELISA, Western Blot
Unconjugated
Mouse
Mouse
Q8K0G8
77411
Anti-Esrp-2 is produced by repeated immunizations of full length recombinant mouse Esrp-2 fusion protein.
Primary
Antibody
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