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Esrp-2 Monoclonal Antibody (22C5.H7.A6), Rockland™

Mouse Monoclonal Antibody
$174.73 - $651.91
Specifications
Antigen | Esrp-2 |
---|---|
Clone | 22C5.H7.A6 |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-1461
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Rockland Immunochemicals
210301C32 |
100 μg |
Each for $651.91
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50-199-1462
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Rockland Immunochemicals
210301C32S |
25 μL |
Each for $174.73
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Description
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody reacts with mouse Esrp-2 protein. A BLAST analysis was used to suggest cross-reactivity with Esrp-2 from mouse based on a 100% homology with the immunizing sequence. Cross-reactivity with Esrp-2 from other sources has not been determined.
RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.Specifications
Esrp-2 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2 | |
9530027K23Rik; Epithelial splicing regulatory protein 2; Esrp2; PP7059; Rbm35b; RNA binding motif protein 35A; RNA binding motif protein 35b; RNA-binding motif protein 35B; RNA-binding protein 35B | |
ESRP2 | |
IgG2a κ | |
-20°C, Avoid Freeze/Thaw Cycles | |
ESRP2 |
22C5.H7.A6 | |
ELISA, Western Blot | |
Unconjugated | |
Mouse | |
Mouse | |
Q8K0G8 | |
77411 | |
Anti-Esrp-2 is produced by repeated immunizations of full length recombinant mouse Esrp-2 fusion protein. | |
Primary | |
Antibody |
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