ESRP1, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA554873

Catalog No. PIPA554873

Description

RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.

Immunogen sequence: QLHVRQILHP EASKKNVLLP ECFYSFFDLR KEFKKCCPGS PDIDKLDVAT MTEYLNFEKS SSVSRYGASQ VEDMGNIILA MISEPYNHRF SDPERVNYKF ESHighest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 93%.

Specifications

• Antigen: ESRP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ESRP1
• Gene Alias: RBM35A, RMB35A, RNA binding motif protein 35A, RNA-binding motif protein 35A, RNA-binding protein 35A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54845
• Content And Storage: Store at 4°C short term. Store at −20°C long term. Avoid freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry
• Concentration: 0.1mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6NXG1
• Gene Symbols: ESRP1
• Immunogen: Recombinant protein corresponding to Human ESRP1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only