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Invitrogen™ ESRP2 Polyclonal Antibody
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Catalog No. PIPA583919
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100 μL
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PIPA583919 100 μL
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Catalog No. PIPA583919 Supplier Invitrogen™ Supplier No. PA583919
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TTVGYLTTPT AALASAPTSV LSQSGALVRM QGVPYTAGMK DLLSVFQAYQ LPADDYTSLM PVGDPPRTVL QAPKEWVCL Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 89%.

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ESRP2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ESRP2
Gene Accession No. Q9H6T0
Gene Alias 9530027K23Rik; Epithelial splicing regulatory protein 2; ESRP2; PP7059; RBM35B; RGD1310855; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA-binding motif protein 35B; RNA-binding protein 35B
Gene Symbols ESRP2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ESRP2. Recombinant protein control fragment (Product #RP-104859).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80004
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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