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Invitrogen™ ESRP2 Polyclonal Antibody
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Catalog No. PIPA5114776
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100 μL
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PIPA5114776 100 μL
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Catalog No. PIPA5114776 Supplier Invitrogen™ Supplier No. PA5114776
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RBM35B.

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ESRP2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene ESRP2
Gene Accession No. Q8K0G8, Q9H6T0
Gene Alias 9530027K23Rik; Epithelial splicing regulatory protein 2; ESRP2; PP7059; RBM35B; RGD1310855; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA-binding motif protein 35B; RNA-binding protein 35B
Gene Symbols ESRP2
Host Species Rabbit
Immunogen A synthesized peptide derived from human ESRP2(Accession Q9H6T0), corresponding to amino acid residues P19-T69.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 77411, 80004
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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