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ESRP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501734001 Shop All Proteintech Group Inc Products
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50-173-4001 150 μL
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Catalog No. 50-173-4001 Supplier Proteintech Group Inc Supplier No. 231171AP150UL
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Description

Rabbit Polyclonal Antibody

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5′ UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

Specifications

Antigen ESRP2
Applications Western Blot
Classification Polyclonal
Concentration 0.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ESRP2
Gene Accession No. Q8K0G8, Q9H6T0
Gene Alias ESRP2, RBM35B, RNA binding motif protein 35B, RNA binding protein 35B
Gene Symbols Esrp2
Host Species Rabbit
Immunogen ESRP2 Fusion Protein Ag19436
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 77411, 80004
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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