ESRP2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2618	100 μL

Catalog No. 50-198-2618 Supplier Bioss Supplier No. BS13108R

Description

Rabbit Polyclonal Antibody

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5′ UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

Specifications

• Antigen: ESRP2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ESRP2
• Gene Accession No.: Q9H6T0
• Gene Alias: 9530027K23Rik; Epithelial splicing regulatory protein 2; Esrp2; PP7059; Rbm35b; RNA binding motif protein 35A; RNA binding motif protein 35b; RNA-binding motif protein 35B; RNA-binding protein 35B
• Gene Symbols: ESRP2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human ESRP2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 80004
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG