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Invitrogen™ ESRRA Polyclonal Antibody
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Catalog No. PIPA528390
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PIPA528390 100 μL
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Catalog No. PIPA528390 Supplier Invitrogen™ Supplier No. PA528390
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T. Predicted reactivity: Mouse (98%), Rat (98%), Dog (98%), Pig (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ESRRA
Applications ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.93 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene ESRRA
Gene Accession No. P11474
Gene Alias ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; ESRRA1; ESRRA2; estrogen receptor related 1; estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor alpha 1; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; LOW QUALITY PROTEIN: steroid hormone receptor ERR1; NR3B1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
Gene Symbols ESRRA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ERR alpha. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2101
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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