Invitrogen™ ESRRA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528390

Catalog No. PIPA528390

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (98%), Rat (98%), Dog (98%), Pig (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1.

Specifications

• Antigen: ESRRA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ESRRA
• Gene Alias: ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; ESRRA1; ESRRA2; estrogen receptor related 1; estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor alpha 1; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; LOW QUALITY PROTEIN: steroid hormone receptor ERR1; NR3B1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2101
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.93 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P11474
• Gene Symbols: ESRRA
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ERR alpha. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG