Invitrogen™ ESRRA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535348

Catalog No. PIPA535348

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1.

Specifications

• Antigen: ESRRA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ESRRA
• Gene Alias: ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; ESRRA1; ESRRA2; estrogen receptor related 1; estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor alpha 1; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; LOW QUALITY PROTEIN: steroid hormone receptor ERR1; NR3B1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2101
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P11474
• Gene Symbols: ESRRA
• Immunogen: KLH conjugated synthetic peptide between 131-159 amino acids from the central region of human ESRRA.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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