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Invitrogen™ ESRRA Recombinant Rabbit Monoclonal Antibody (SC57-07)
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Catalog No. PIMA532194
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PIMA532194 100 μL
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Catalog No. PIMA532194 Supplier Invitrogen™ Supplier No. MA532194
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1.
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Specifications

Antigen ESRRA
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone SC57-07
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene ESRRA
Gene Accession No. O08580, P11474, Q5QJV7
Gene Alias ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; ESRRA1; ESRRA2; estrogen receptor related 1; estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor alpha 1; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; LOW QUALITY PROTEIN: steroid hormone receptor ERR1; NR3B1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
Gene Symbols ESRRA
Host Species Rabbit
Immunogen Synthetic peptide within Human Estrogen Related Receptor alpha aa 1-49.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2101, 26379, 293701
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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