ESRRB Monoclonal Antibody (OTI12B7), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-0791	100 μL

Catalog No. 50-168-0791 Supplier OriGene Supplier No. TA805646

Description

Mouse Monoclonal Antibody

ESRRB (steroid hormone receptor ERR2) plays a role in maintaice of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells. ESSRB also regulates expression of multiple rod-specific genes and is required for survial of this cell type. Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35).

Specifications

• Antigen: ESRRB
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI12B7
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: ESRRB
• Gene Accession No.: O95718
• Gene Alias: DFNB35, ERR2, ERRb, ESRL2, NR3B2
• Gene Symbols: ESRRB
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-252 of human ESRRB produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2103
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b