ESRRB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3910	Proteintech Group Inc 226441AP150UL	150 μL

Description

ESRRB (steroid hormone receptor ERR2) plays a role in maintaice of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells. ESSRB also regulates expression of multiple rod-specific genes and is required for survial of this cell type. Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35).

Specifications

• Antigen: ESRRB
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O95718, P11475, Q61539
• Gene ID (Entrez): 2103, 26380, 299210
• Immunogen: ESRRB Fusion Protein Ag18523
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ESRRB

• Concentration: 0.5 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: DFNB35, ERR2, ERRb, ERRbeta, ERRbeta 2, ESRL2, ESRRB, ESRRB protein, estrogen related receptor beta, NR3B2
• Gene Symbols: ESRRB
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody