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β-Estradiol, MP Biomedicals™

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Quantity:
250mg
50-28-2
C18H24O2
272.388
VOXZDWNPVJITMN-ZBRFXRBCSA-N
estradiol,beta-estradiol,17beta-estradiol,oestradiol,dihydrofolliculin,estrace,ovocyclin,progynon,dihydrotheelin,dihydroxyestrin
5757
CHEBI:16469
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
50-28-2
C18H24O2
272.388
VOXZDWNPVJITMN-ZBRFXRBCSA-N
estradiol,beta-estradiol,17beta-estradiol,oestradiol,dihydrofolliculin,estrace,ovocyclin,progynon,dihydrotheelin,dihydroxyestrin
5757
CHEBI:16469
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O

β-Estradiol is a potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins, leading to ovulation.

Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation.

  • The major estrogen secreted by the premenopausal ovary.
  • Exposure to estradiol increases breast cancer incidence and proliferation.
Melting Point 173°C to 179°C
Quantity 250mg
Optical Rotation +76.8 (Concentration = 1, Solvent = Dioxane) (Lit.)
Solubility Information Almost insoluble in water (50mg/mL; clear, colorless solution). Freely soluble in alcohol; soluble in acetone, dioxane, other organic solvents; solutions of fixed alkali hydroxides; sparingly soluble in vegetable oils; soluble in methanol:CHCl3 (1:1).
Formula Weight 272.39g/mol
Physical Form White Powder
Grade Cell Culture Reagent

Recommended Storage : Store at Room Temperature (15–30°C). Store under nitrogen.