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  6. Epredia™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody

Epredia™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody

Catalog No. MS391S1 Shop All Epredia Products
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100 μL
500 μL
1 mL
7 mL
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Prediluted
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Catalog No. Quantity Form
MS391S1 500 μL Concentrated
MS391S0 100 μL Concentrated
MS391R1 1 mL Prediluted
MS391R7 7 mL Prediluted
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Catalog No. MS391S1 Supplier Epredia™ Supplier No. MS391S1
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Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: 6F11

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Immunogen: Recombinant full-length estrogen receptor protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Estrogen Receptor Ab-12
Applications Immunoprecipitation
Classification Monoclonal
Clone 6F11
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant full length estrogen receptor protein
Purification Method MCF-7 cells, breast CA
Quantity 500 μL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Primary or Secondary Primary
Target Species Human, Rat
Form Concentrated
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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