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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Manufacturer:  Thermo Scientific™ RB1521P1

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Catalog No. RB1521P1


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Description

Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody.

ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Rat, Mouse, Rabbit, Sheep, Pig and Cow. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminus of human estrogen receptor, α protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Estrogen Receptor Ab-17
Polyclonal
1mg/mL
Purified Ab with BSA and Azide
Rabbit
IgG
RUO
Primary
Polyclonal
Immunoprecipitation, Western Blot
Polyclonal
Unconjugated
Concentrated
A synthetic peptide from the N-terminus of human estrogen receptor, alpha protein
500μL
Steroids Hormones and Growth Factors
Primary
Bovine, Human, Murine, Porcine, Rabbit, Rat
SDS
Documents
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