ETF1 Mouse anti-Human, Clone: OTI2E3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF502891

Catalog No. 50-166-1713

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA; however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons.

Specifications

• Antigen: ETF1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ETF1
• Gene Alias: D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2107
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Clone: OTI2E3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P62495
• Gene Symbols: ETF1
• Immunogen: Full length human recombit protein of human ETF1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a