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Invitrogen™ ETV1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA577975
Description
Positive Control: A431, Rat2 Predicted Reactivity: Xenopus laevis (86%), Chicken (92%), Chimpanzee (100%), Bovine (95%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
Specifications
ETV1 | |
Polyclonal | |
Unconjugated | |
Etv1 | |
DKFZp781L0674; Er81; ets related protein 81; ETS transcription factor Er81; ETS translocation variant 1; ets variant 1; ets variant gene 1; ETS variant transcription factor 1; ets-related protein 81; Etsrp81; Etv1; MGC104699; MGC120533; MGC120534; MGC137631 protein | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
14009, 2115, 362733 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.34 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
P41164, P50549 | |
Etv1 | |
Recombinant protein encompassing a sequence within the center region of human ER81. The exact sequence is proprietary. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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