Invitrogen™ ETV6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528286

Catalog No. PIPA528286

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (89%), Rat (95%), Chicken (86%), Rhesus Monkey (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and Maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Specifications

• Antigen: ETV6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Etv6
• Gene Alias: AW123102; AW557856; CGI-108; CSL4; Csl4p; ETS translocation variant 6; ETS variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; Etv6; hCsl4p; p13; RP11-452K12.9; SKI4; Ski4p; Tel; TEL/ABL; Tel1; TEL1 oncogene; THC5; Transcription factor ETV6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2120
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.62 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P41212
• Gene Symbols: Etv6
• Immunogen: Recombinant protein encompassing a sequence within the center region of human TEL. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov