EVER2/TMC8 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2627	100 μL

Catalog No. 50-198-2627 Supplier Bioss Supplier No. BS13116R

Description

Rabbit Polyclonal Antibody

Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.

Specifications

• Antigen: EVER2/TMC8
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: TMC8
• Gene Accession No.: Q8IU68
• Gene Alias: epidermodysplasia verruciformis 2; Epidermodysplasia verruciformis protein 2; Epidermodysplasia verruciformis protein 2 homolog; EV2; EVER2; EVIN2; mFLJ00400; TMC8; transmembrane channel like 8; transmembrane channel-like 8; transmembrane channel-like gene family 8; Transmembrane channel-like protein 8
• Gene Symbols: TMC8
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human EVER2/TMC8.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 147138
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG