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Invitrogen™ EVI1 Monoclonal Antibody (S.446.4)
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Catalog No. PIMA514892
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100 μL
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PIMA514892 100 μL
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Catalog No. PIMA514892 Supplier Invitrogen™ Supplier No. MA514892
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Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

EVI1 (MECOM) is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression of the EVI1 gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EVI1
Applications Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone S.446.4
Concentration 651 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 50% glycerol, 0.15M NaCl, 100μg/mL BSA and <0.02% sodium azide; pH 7.5
Gene MECOM
Gene Accession No. Q03112
Gene Alias AML1-EVI-1; AML1-EVI-1 fusion protein; D630039M04Rik; ecotropic viral integration site 1; ecotropic virus integration site 1 protein; Ecotropic virus integration site 1 protein homolog; EVI1; Evi-1; Histone-lysine N-methyltransferase MECOM; Jbo; Mds; MDS1; MDS1 and EVI1 complex locus; MDS1 and EVI1 complex locus protein; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; Mds1-Evi1; Mecom; MGC163392; MGC97004; myelodysplasia syndrome 1 homolog; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome 1 protein homolog; myelodysplasia syndrome-associated protein 1; oncogene EVI1; OTTHUMP00000213163; OTTHUMP00000213164; OTTHUMP00000213165; OTTHUMP00000213187; OTTHUMP00000213192; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1; Znfpr1b1
Gene Symbols MECOM
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding Asp57 of human Evi-1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2122
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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