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Invitrogen™ EWSR1 Polyclonal Antibody, Biotin
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Catalog No. PIPA5142450
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100 μg
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PIPA5142450 100 μg
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Catalog No. PIPA5142450 Supplier Invitrogen™ Supplier No. PA5142450
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize all five reported isoforms (NP_053733.2; NP_005234.1; NP_001156757.1; NP_001156758.1; NP_001156759.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a ttranslocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EWSR1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene EWSR1
Gene Accession No. Q01844
Gene Alias AC002059.7; bK984G1.4; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma homolog; Ewings sarcoma EWS-Fli1 (type 1) oncogene; Ews; EWS oncogene; EWS RNA binding protein 1; EWS RNA-binding protein 1; EWS RNA-binding protein variant 6; EWS-FLI1; Ewsh; EWSR1; RNA-binding protein EWS
Gene Symbols EWSR1
Host Species Goat
Immunogen Peptide with sequence C-TSYDQSSYSQQNTYG (aa 201-215).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2130
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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