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EXD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501731502 Shop All Proteintech Group Inc Products
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50-173-1502 150 μL
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Catalog No. 50-173-1502 Supplier Proteintech Group Inc Supplier No. 173131AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody can recognize all these three isoforms.

EXD1 is an RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease.

Specifications

Antigen EXD1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene EXD1
Gene Accession No. Q8CDF7, Q8NHP7
Gene Alias EXD1, EXDL1
Gene Symbols Exd1
Host Species Rabbit
Immunogen EXD1 Fusion Protein Ag11282
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 161829, 241624, 311334
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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