Invitrogen™ EXO5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110957

Catalog No. PIPA5110957

Description

Immunogen sequence: ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG.

Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'- directionality activity.

Specifications

• Antigen: EXO5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Exo5
• Gene Alias: 3110037I16Rik; AV297100; C1orf176; defects in morphology 1 homolog; defects in morphology protein 1 homolog; Defects in morphology protein 1-like; Dem1; Exo V; EXO5; exonuclease 5; exonuclease V; hExo5; mExo5; probable exonuclease V
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64789
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H790
• Gene Symbols: Exo5
• Immunogen: Recombinant Protein corresonding to Human EXO5. Recombinant protein control fragment (Product #RP-94441).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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