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Invitrogen™ EXO5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5110957
Description
Immunogen sequence: ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG.
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'- directionality activity.
Specifications
EXO5 | |
Polyclonal | |
Unconjugated | |
Exo5 | |
3110037I16Rik; AV297100; C1orf176; defects in morphology 1 homolog; defects in morphology protein 1 homolog; Defects in morphology protein 1-like; Dem1; Exo V; EXO5; exonuclease 5; exonuclease V; hExo5; mExo5; probable exonuclease V | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
64789 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot, Immunocytochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9H790 | |
Exo5 | |
Recombinant Protein corresonding to Human EXO5. Recombinant protein control fragment (Product #RP-94441). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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