Invitrogen™ EXOC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531826

Catalog No. PIPA531826

Description

Recommended positive controls: A431, HeLa. Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (83%), Chicken (93%), Rhesus Monkey (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.

Specifications

• Antigen: EXOC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Exoc2
• Gene Alias: 2410030I24Rik; AI648199; Exoc2; Exocyst complex component 2; Exocyst complex component 2-like protein; exocyst complex component Sec5; rSec5; Sec5; SEC5 homolog; Sec5 protein; Sec5l1; SEC5-like 1; Sec5p
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55770
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96KP1
• Gene Symbols: Exoc2
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human EXOC2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov