Invitrogen™ EXOC4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588508

Catalog No. PIPA588508

Description

Immunogen sequence: MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA YEKCDRDLDE LIVQHYTELT TAIRTYQSIT ERITNSRNKI KQVKENLLSC KMLLHCKRDE LRKLWIEGIE HKHVLNLLDE IENIKQVPQK LEQCMASKHY LSATDMLVSA VESLEGPLLQ VEGLSDLRLE LHSKKMNLHL VLIDELHRHL YIKSTSRVVQ RNKEKGKISS LVKDASVPLI DVTNLPTPRK FLDTSHYSTA GSSSVREINL QDIKEDLELD PEENSTLFMG; Positive Samples: A-431, Jurkat, Mouse brain, Mouse thymus, Mouse liver, Rat brain.

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: EXOC4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EXOC4
• Gene Alias: ALR; augmenter of liver regeneration (ALR) pseudogene; C78892; Exoc4; Exocyst complex component 4; exocyst complex component 4 tv1; Exocyst complex component 4-like protein; exocyst complex component Sec8; KIAA1699; LOW QUALITY PROTEIN: exocyst complex component 4; MGC27170; REC8; rSec8; Sec8; SEC8 protein; Sec8l1; SEC8-like 1; Sec8p; secretory protein SEC8; si:ch211-92l17.2; si:rp71-18a24.2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116654, 20336, 60412
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.92 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O35382, Q62824, Q96A65
• Gene Symbols: EXOC4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_0685793).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov