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Invitrogen™ EYA2 Polyclonal Antibody
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Catalog No. PIPA566243
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100 μL
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Catalog No. Quantity
PIPA566243 100 μL
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Catalog No. PIPA566243 Supplier Invitrogen™ Supplier No. PA566243
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MVELVISPSLT VNSDCLDKLK FNRADAAVWT LSDRQGITKS APLRVSQLFS RSCPRVLPRQ PSTAMAAYGQ TQYSAGIQQA TPYTAYPPPA QAYGIPSYSI Highest antigen sequence identity to the following orthologs - mouse 67%, rat 63%.

Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EYA2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EYA2
Gene Accession No. O00167
Gene Alias Drosophila-type eyes absent 2-like protein; Eab1; EYA transcriptional coactivator and phosphatase 2; Eya2; eyes absent 2; eyes absent 2 homolog; eyes absent 2 homolog (Drosophila); eyes absent 2 isoform a; eyes absent homolog 2
Gene Symbols EYA2
Host Species Rabbit
Immunogen Recombinant Human EYA2. Recombinant protein control fragment (Product #RP-105124).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2139
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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