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EYA2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982634
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50-198-2634 100 μL
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Catalog No. 50-198-2634 Supplier Bioss Supplier No. BS13125R
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Description

Rabbit Polyclonal Antibody

Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates ′Tyr- 142′ of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. ′Tyr-142′ phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.

Specifications

Antigen EYA2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene EYA2
Gene Accession No. O00167
Gene Alias BOS_13470; Drosophila-type eyes absent 2-like protein; EAB1; EYA transcriptional coactivator and phosphatase 2; Eya2; eyes absent 2; eyes absent 2 homolog; eyes absent 2 homolog (Drosophila); Eyes absent homolog 2; eyes absent homolog 2 (Drosophila); LOC100355981
Gene Symbols EYA2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human EYA2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2139
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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