Invitrogen™ EYA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558534

Catalog No. PIPA558534

Description

Immunogen sequence: QYAQYYSAST YGAYMTSNNT ADGTPSSTST YQLQESLPGL TNQPGEFDTM QSPSTPIKDL DERTCRSSGS KS Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: EYA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EYA4
• Gene Alias: B130023L16Rik; CMD1J; DFNA10; dJ78N10.1 (eyes absent); EYA transcriptional coactivator and phosphatase 4; EYA4; eyes absent 4 homolog (Drosophila); eyes absent homolog 4; eyes absent-like protein 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14051, 2070, 292172
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95677, Q9Z191
• Gene Symbols: EYA4
• Immunogen: Recombinant protein corresponding to Human EYA4. Recombinant protein control fragment (Product #RP-94980).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG