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Invitrogen™ EZH2 Polyclonal Antibody
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Catalog No. PIPA5120945
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100 μL
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PIPA5120945 100 μL
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Catalog No. PIPA5120945 Supplier Invitrogen™ Supplier No. PA5120945
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Description

Rabbit Polyclonal Antibody

Positive test controls include: MCF7, C6, HeLa, Mouse brain. The target is usually found in the following locations: Nucleus. Immunogen sequence: YMGDEVLDQD GTFIEELIKN YDGKVHGDRE CGFINDEIFV ELVNALGQYN DDDDDDDGDD PEEREEKQKD LEDHRDDKES RPPRKFPSDK IFEAISSMFP DKGTAEELKE KYKELTEQQL.

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen EZH2
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene EZH2
Gene Accession No. Q15910, Q61188
Gene Alias an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2
Gene Symbols EZH2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 133-252 of human EZH2/KMT6 (NP_001190176.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14056, 2146, 312299
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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