Ezrin Monoclonal Antibody (3C12), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA513862

Catalog No. PIMA513862

Description

MA5-13862 targets Ezrin in IHC (P), ICC, IP, IF, and WB applications and shows reactivity with Bovine, Hamster, Human, Marsupial, mouse, Non-human primate, and Rat samples. The MA5-13862 immunogen is a recombinant fragment of human ezrin corresponding to aa 362-585.

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Specifications

• Antigen: Ezrin
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P15311, P26040, P31976, P31977
• Gene Symbols: Ezr
• Immunogen: A recombinant fragment of human ezrin corresponding to aa 362-585
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Hamster, Human, Marsupial, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 3C12
• Conjugate: Unconjugated
• Gene: Ezr
• Gene Alias: AW146364; CVIL; CVL; Cytovillin; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; ezr; ezr.L; ezr.S; EZRI; Ezrin; ezrin L homeolog; ezrin L homeolog; ezrin S homeolog; FLJ26216; HEL-S-105; MGC1584; p81; R75297; VIL2; villin 2; villin 2 (ezrin); villin-2; XELAEV_18027043mg
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100762541, 22350, 281574, 54319, 7430
• Content And Storage: 4° C
• Form: Liquid