Invitrogen™ Ezrin Recombinant Rabbit Monoclonal Antibody (037)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA529252

Catalog No. PIMA529252

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human Ezrin/villin 2.

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Specifications

• Antigen: Ezrin
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P15311
• Gene Symbols: Ezr
• Immunogen: Recombinant Human Ezrin/villin 2 Protein (Pro2-Leu586).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Clone: 037
• Conjugate: Unconjugated
• Gene: Ezr
• Gene Alias: AW146364; CVIL; CVL; Cytovillin; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; ezr; ezr.L; ezr.S; EZRI; Ezrin; ezrin L homeolog; ezrin L homeolog; ezrin S homeolog; FLJ26216; HEL-S-105; MGC1584; p81; R75297; VIL2; villin 2; villin 2 (ezrin); villin-2; XELAEV_18027043mg
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7430
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid