F11R Mouse anti-Human, Clone: OTI6E11, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA506034

Catalog No. 50-167-6403

Description

CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintece of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.

Specifications

• Antigen: F11R
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9Y624
• Gene Symbols: F11R
• Immunogen: Full length human recombit protein of human F11R produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI6E11
• Conjugate: Unconjugated
• Gene: F11R
• Gene Alias: CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50848
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid