Invitrogen™ F131C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570162

Catalog No. PIPA570162

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

F131C gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk.

Specifications

• Antigen: F131C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM131C
• Gene Alias: C1orf117; FAM131C; family with sequence similarity 131 member C; family with sequence similarity 131, member C; Gm693; hypothetical protein LOC619198; protein FAM131C; RP11-5P18.9; zgc:110264
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 348487
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q96AQ9
• Gene Symbols: FAM131C
• Immunogen: synthetic peptide directed towards the middle region of human F131C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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