Invitrogen™ FABP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580610

Catalog No. PIPA580610

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human FABP3/H-FABP.

Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.

Specifications

• Antigen: FABP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FABP3
• Gene Alias: 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3; FABP11; Fabp3; Fabph1; Fabph-1; Fabph4; Fabph-4; fatty acid binding protein 11; Fatty acid binding protein 11 (FABP11); fatty acid binding protein 3; Fatty acid binding protein 3 heart; fatty acid binding protein 3, muscle and heart; Fatty acid binding protein heart; fatty acid binding protein heart 1; fatty acid binding protein heart 4; fatty acid-binding protein 3; Fatty acid-binding protein, heart; heart FABP; heart fatty acid binding protein; Heart type fatty acid binding protein; heart-type fatty acid-binding protein; H-FABP; M FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; M-FABP; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle fatty acid-binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte; O-FABP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P05413
• Gene Symbols: FABP3
• Immunogen: A synthetic peptide corresponding to the C-terminus of the Human FABP3/H-FABP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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