Invitrogen™ FABP7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531864

Catalog No. PIPA531864

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, mouse brain, mouse fetal brain, rat brain. Predicted reactivity: Mouse (87%), Rat (88%), Japanese Medaka (85%), Xenopus laevis (86%), Pig (96%), Chicken (91%), Rhesus Monkey (97%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.

Specifications

• Antigen: FABP7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FABP7
• Gene Alias: B FABP; BFABP; B-FABP; BLBP; brain lipid binding protein; brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; FABP7; FABPB; fatty acid binding protein 7; fatty acid binding protein 7, brain; fatty acid-binding protein 7; Fatty acid-binding protein, brain; fatty acid-binding protein, brain-like protein; hypothetical protein DKFZp547J2313; Mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; MRG; OTTHUMP00000017119; RP11-548E19.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12140, 2173, 80841
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O15540, P51880, P55051
• Gene Symbols: FABP7
• Immunogen: Full length human FABP7 Recombinant protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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