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Invitrogen™ Factor V Monoclonal Antibody (5112)
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Catalog No. PIMA143004
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100 μg
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Catalog No. Quantity
PIMA143004 100 μg
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Catalog No. PIMA143004 Supplier Invitrogen™ Supplier No. MA143004
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Mouse Monoclonal Antibody

MA1-43004 detects human factor Va light chain (fragment E, 74000). Does not react with intact Factor V. MA1-43004 has successfully been used in RIA and Western blot applications. MA1-43004 was derived from purified human factor V.

Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Factor V
Applications Radioimmune Assays (RIA), Western Blot
Classification Monoclonal
Clone 5112
Concentration 8.7 mg/mL
Conjugate Unconjugated
Formulation 50% water with 50% glycerol and no preservative
Gene F5
Gene Accession No. P12259
Gene Alias Ac2-120; Activated protein C cofactor; AI173222; Cf5; Cf-5; coagulation factor V; coagulation factor V (proaccelerin, labile factor); Coagulation factor V heavy chain; coagulation factor V jinjiang A2 domain; Coagulation factor V light chain; F5; Factor 5; factor V; factor V Leiden; Factor5; FVL; PCCF; Proaccelerin, labile factor; RPRGL1; THPH2
Gene Symbols F5
Host Species Mouse
Immunogen Purified human factor V.
Purification Method SDS-PAGE
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2153
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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